Chromatin Dynamics and Cytoskeletal Rearrangements

The lab research is focused on the interrelations between cytoplasmic cytoskeletal rearrangements and chromatin structure and function inside the nucleus. We have found that induction of tumor cell migration induces global chromatin condensation, which is a prerequisite for proper cell migration. We also showed that major changes in cytoplasmic microtubules alter the nuclear envelope morphology as well as the global organization of the chromatin fibers.

Dr. Gabi Gerlitz

Gabi Gerlitz is a senior lecturer in the department of Molecular Biology in Ariel University. Dr. Gerlitz received his B.Sc. from Tel Aviv University. His M.Sc. and Ph.D. studies on the regulation of protein synthesis were done in the department of Cell Research and Immunology at Tel Aviv University. He did postdoctoral work on cell migration and chromatin dynamics in the department of Molecular Genetics at the Weizmann Institute of Science, Israel and the Laboratory of Metabolism, NCI, MD, USA.